Patent covers active pharmaceutical ingredient with protection until 2041 ANNAPOLIS, Md., Oct. 27, 2025 /PRNewswire/ -- Alphyn, a clinical-stage dermatology company developing first-in-class Multi-Target Therapeutics®, announced today that the U.S. Patent and Trademark Office (USPTO) has granted a patent for the active pharmaceutical ingredient (API) in its lead candidate for atopic dermatitis (AD). The patent complements Alphyn's previously issued U.S. patent protecting its Zabalafin Hydrogel drug products and expands the company's broader intellectual property portfolio.